Interactive InterPro-based comparisons of proteins in whole genomes
نویسندگان
چکیده
MOTIVATION The SWISS-PROT group at the EBI has developed the Proteome Analysis Database utilizing existing resources and providing comprehensive and integrated comparative analysis of the predicted protein coding sequences of the complete genomes of bacteria, archaea and eukaryotes. The Proteome Analysis Database is accompanied by a program that has been designed to carry out interactive InterPro proteome comparisons for any one proteome against any other one or more of the proteomes in the database.
منابع مشابه
Proteome Analysis Database: online application of InterPro and CluSTr for the functional classification of proteins in whole genomes
The SWISS-PROT group at EBI has developed the Proteome Analysis Database utilising existing resources and providing comparative analysis of the predicted protein coding sequences of the complete genomes of bacteria, archaea and eukaryotes (http://www.ebi.ac. uk/proteome/). The two main projects used, InterPro and CluSTr, give a new perspective on families, domains and sites and cover 31-67% (In...
متن کاملThe Proteome Analysis database: a tool for the in silico analysis of whole proteomes
The Proteome Analysis database (http://www.ebi.ac.uk/proteome/) has been developed by the Sequence Database Group at EBI utilizing existing resources and providing comparative analysis of the predicted protein coding sequences of the complete genomes of bacteria, archeae and eukaryotes. Three main projects are used, InterPro, CluSTr and GO Slim, to give an overview on families, domains, sites, ...
متن کاملApplications of InterPro in Protein Annotation and Genome Analysis
The applications of InterPro span a range of biologically important areas that includes automatic annotation of protein sequences and genome analysis. In automatic annotation of protein sequences InterPro has been utilised to provide reliable characterisation of sequences, identifying them as candidates for functional annotation. Rules based on the InterPro characterisation are stored and opera...
متن کاملInterPro: Quick tour
Classifying proteins into families and identifying important domains and sites is invaluable for helping biologists to identify distantly related proteins and to predict their functions. A daunting array of resources, each with different strengths and weaknesses, is now available for searching genomes and proteomes with ‘protein signatures’ – diagnostic entities that are used to recognise a par...
متن کاملInterPro in 2011: new developments in the family and domain prediction database
InterPro (http://www.ebi.ac.uk/interpro/) is a database that integrates diverse information about protein families, domains and functional sites, and makes it freely available to the public via Web-based interfaces and services. Central to the database are diagnostic models, known as signatures, against which protein sequences can be searched to determine their potential function. InterPro has ...
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عنوان ژورنال:
- Bioinformatics
دوره 18 2 شماره
صفحات -
تاریخ انتشار 2002